Staphylococci in Human Disease, Second Edition

There is now a much greater understanding of the physiology and evolution of the staphylococci and this new edition reflects the rapid advancements in knowledge about this pathogen and provides a comprehensive review from both clinical and basic science perspectives.

The first section addresses the basic biology of the staphylococci, their molecular genetics, host defenses and host evasion, virulence determinants, mechanisms of antibiotic resistance, and laboratory techniques. The second section deals with epidemiology, and the third section provides an overview of the varied clinical manifestations of human staphylococcal infections. The fourth section covers prevention and treatment of these often life-threatening infections.

Written by experts from around the globe, this book is essential reading for all clinicians and basic scientists studying the staphylococci.Content:
Chapter 1 The Biology of Staphylococci (pages 1–18): Greg A. Somerville and Richard A. Proctor
Chapter 2 Genomics of the Staphylococci (pages 19–30): Steven R. Gill
Chapter 3 Evolution and Taxonomy of Staphylococci (pages 31–64): Barun Mathema, Jose R. Mediavilla, Liang Chen and Barry N. Kreiswirth
Chapter 4 Molecular Basis of Pathogenicity (pages 65–108): Mark S. Smeltzer, Chia Y. Lee, Nada Harik and Mark E. Hart
Chapter 5 Adaptation to Stress: Biofilms and Small?Colony Variants (pages 109–124): Karl M. Thompson and Kimberly K. Jefferson
Chapter 6 Exotoxins (pages 125–146): Patrick M. Schlievert, John K. McCormick, Gregory A. Bohach and Douglas H. Ohlendorf
Chapter 7 Host Defense against Staphylococcal Infection (pages 147–169): Hattie D. Gresham and Timothy J. Foster
Chapter 8 Resistance to ??Lactam Antibiotics (pages 170–192): Brigitte Berger?Bachi, Maria Magdalena Senn, Miriam Ender, Kati Seidl, Judith Hubscher, Bettina Schulthess, Roni Heusser, Patricia Stutzmann Meier and Nadine McCallum
Chapter 9 Resistance to Glycopeptides (pages 193–209): Keiichi Hiramatsu
Chapter 10 Resistance to Other Agents (pages 210–234): Jacob Strahilevitz and David C. Hooper
Chapter 11 Issues in the Identification and Susceptibility Testing of Staphylococci (pages 235–252): Betty A. Forbes
Chapter 12 Colonization with Staphylococcus Aureus and the Role of Colonization in Causing Infection (pages 253–271): Henri A. Verbrugh
Chapter 13 Epidemiology of Community?Associated Staphylococcus Aureus Infections (pages 272–289): Rachel J. Gorwitz and John A. Jernigan
Chapter 14 Epidemiology of Healthcare?Associated Staphylococcus Aureus Infections (pages 290–309): Andrew E. Simor and Mark Loeb
Chapter 15 Epidemiology of Coagulase?Negative Staphylococci and Infections Caused by These Organisms (pages 310–332): Kathie L. Rogers, Paul D. Fey and Mark E. Rupp
Chapter 16 Staphylococcus aureus Bacteremia and Endocarditis (pages 333–345): Zeina A. Kanafani, Sara E. Cosgrove and Vance G. Fowler
Chapter 17 Surgical?Site Infections and Surgical Prophylaxis (pages 346–362): Deverick J. Anderson and Keith S. Kaye
Chapter 18 Infections of Intravascular Catheters and Vascular Devices (pages 363–377): Hidetaka Yanagi and Robert J. Sherertz
Chapter 19 Skin and Soft Tissue Infections (pages 378–394): Martin E. Stryjewski, Esteban C. Nannini and G. Ralph Corey
Chapter 20 Central Nervous System Infections (pages 395–413): Karen L. Roos
Chapter 21 Diseases of the Eye (pages 414–423): Linda A. Ficker
Chapter 22 Osteomyelitis and Other Bone and Joint Infections (pages 424–443): Odette C. El Helou, Elie F. Berbari and Douglas R. Osmon
Chapter 23 Staphylococcal Pneumonia (pages 444–454): Ethan Rubinstein and Marin H. Kollef
Chapter 24 Urinary Tract Infections (pages 455–469): S. Gatermann and Kent B. Crossley
Chapter 25 Toxic Shock Syndrome (pages 470–483): Aaron Devries
Chapter 26 Toxin?Mediated Syndromes (pages 484–496): Tristan Ferry and Jerome Etienne
Chapter 27 Staphylococcal Diarrhea and Enterocolitis (pages 497–504): Mark H. Wilcox
Chapter 28 Infections in Immunocompromised Patients (pages 505–520): Lisa E. Davidson and Helen W. Boucher
Chapter 29 Clinical Manifestations of Community?Acquired MRSA Infections (pages 521–537): Brian S. Schwartz and Henry F. Chambers
Chapter 30 Elimination of Staphylococcus Aureus Carriage: Importance and Strategies (pages 539–569): Loreen A. Herwaldt and John M. Boyce
Chapter 31 Treatment of Staphylococcal Infections (pages 570–593): Kent B. Crossley and Joseph John
Chapter 32 Vaccine?Based Strategies for Prevention of Staphylococcus Aureus Infection (pages 594–611): Adam C. Schaffer and Jean C. Lee